Scardovia wiggsiae and Streptococcus sobrinus Prevalence among Orthodontic and Non-Orthodontic Patients

Background: Dental cavities or caries have been identified as among the most prevalent of preventable oral conditions. However, studies are discovering new information regarding incidence and prevalence several cariogenic organisms, including Streptococcus mutans (SM), recently discovered Scardovia wiggsiae (SW), well sobrinus (SS). These revealed varying different populations, such those undergoing orthodontic treatment. Based upon this information, main goal current study was to assess specific organisms (SS SW) within saliva samples originally obtained from a dental school-based clinic.
 Methods: The protocol for retrospective DNA isolated previously collected reviewed approved by Institutional Review Board (IRB) exempt research. In brief, clinical were screened SS SW using quantitative polymerase chain reaction (qPCR). Demographic subgroup (Orthodontic, non-Orthodontic) analysis also performed.
 Results: This found that pediatric (12-17 year old patient) much more likely harbor either compared with adult (>18 samples. addition, many SW-positive patients non-Orthodontic patients, which may suggest population be at higher risk SW-related other negative health outcomes. Finally, these microbial populations strongly linked same patient samples.
 Conclusions: has demonstrated highly associated subgroups, observed in non-orthodontic patients. results differ previous evidence, only minor partially overlapping microbes. correlated similar communities their presence directly indirectly through one behavioral, factors – although research will needed determine mechanisms.